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January 2020
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University of Bath & Pharmacy Practice Research Trust Press Release

A new report published by the Pharmacy Practice Research Trust (The Trust) suggests that care for people with Alzheimer’s disease and dementia needs to be more holistic in its approach, and that the assessment tools used for treatment options are not sensitive enough.

Whilst cognitive function can be improved by the medicines currently available for the treatment of dementias, the report says the positive effects of improved socialibility, initiative and motivation on the patient and their carer as well as their capability of coping with everyday life should not be overlooked.

Denise Taylor, Senior Teaching Fellow in the Department of Pharmacy & Pharmacology at the University of Bath, explored patient and carer perspectives whilst using medicines for dementia, and their impact on coping with day-to-day life.

The research showed that the wider improvement in personality achieved by the medicines for dementia such as improved social skills, orientation and initiative, which positively affected personal and wider relationships, outweighed the improvements in memory.

The study, commissioned by the Trust and supported by a Galen Award, also identified a need for improved information for carers about how a dementia can affect an individual and the changed behaviours that can result.

Ms Taylor said: “Carers need to know that these are part of the disease and not a deliberate action on the part of the person with dementia.”

The research emphasises the extent to which medication is often not an option for people in early to mid stages of dementia and how important support is for these patients and their carers.

Through a series of case studies involving the patient, their carer and the associated professional team over 13 months, the study highlights some of the real issues faced by all those involved in the care of people with dementia especially when other health problems are present such as hearing or eyesight difficulties.

The spouses of those with dementia all described in various ways how difficult they found it living with this different person who wasn’t the same one they married, and wondered if it was the end of their lives as they knew it.

One carer described how all their friends seemed to “disappear” after the diagnosis and others became embarrassed going out with a partner who just sat beside or across from them and said absolutely nothing.

Ms Taylor added: “My study also showed that patients rarely fit the assessment measurements used to guide treatment as recommended by NICE, such as the Mini Mental State Examination.

“This was shown to be telling only half the story and did not accurately reflect for some participants the true impact of their dementia or their medication on their day-to-day life.”

Commenting on the research, Beth Allen, Acting Director of the Trust, said: “Although no pharmacists were recruited to this study, they could play a part in the support of people with dementia and their families.

“This could be through the provision of information and reviewing medicine use to ensure the most effective use of medication, support with compliance and titration regimens.”

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